Harry Fluder’s (Bryan Greenberg) life was working out exactly as planned: great job, loyal friends, and the perfect fiancee – until he caught his perfect fiancee having sex with one of his loyal friends at their wedding. With the wedding cancelled and honeymoon already paid for, Bowie (Brooks Whelan), Harry's best man, convinces Harry to take him along on a "homie-moon." What is supposed to be a refreshing weekend of rest and relaxation turns into an all-out bonkers adventure of epic proportions of sex, drugs, and mafia intrigue. Kyle Kinane, Spencer Grammer, Joe Pantoliano, Brittany Furlan and more round out this madcap comedy’s stellar cast.